A summary of the Company's option activity related to options to employees and directors, and related information is as follows:

 

		For the nine months ended September 30, 2014
		Amount of options			Weighted average exercise price			Aggregate intrinsic value
					$			$
Outstanding at beginning of period			412,389			2.5576
Granted			433,333			4.1539
Exercised			(13,333)			2.2500
Cancelled			(66,500)			2.1250
Outstanding at end of period			765,889			3.5037			464,393
Vested and expected-to-vest at end of period			360,389			2.5342			567,888

The total stock-based compensation expense, related to shares, options and warrants granted to employees, directors and service providers, was comprised, at each period, as follows:

 

		Nine months ended						Three months ended
		September 30,						September 30,
		2014			2013			2014			2013
		Unaudited						Unaudited
Research and development			160			101			16			7
General and administrative			604			521			339			(71)
Total stock-based compensation expense			764			622			355			(64)