Income Taxes - Schedule of Reconciliation of Federal Statutory Income Tax Rate to Effective Tax Rate (Detail)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Effective Income Tax Rate Reconciliation [Line Items]    
Statutory Federal income tax rate 34.00% 34.00%
State income taxes - net of Federal tax benefit 0.80% 1.50%
Other permanent differences (8.10%) (3.50%)
Valuation allowances (37.00%) (40.20%)
Effective tax rate for the year 0.20% 0.20%
U.S. Federal [Member]    
Effective Income Tax Rate Reconciliation [Line Items]    
Research and development 10.30% 8.20%
Foreign [Member]    
Effective Income Tax Rate Reconciliation [Line Items]    
Research and development 0.20% 0.20%