Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands |
12 Months Ended |
Dec. 31, 2016 |
Dec. 31, 2015 |
Dec. 31, 2014 |
| Revenues |
|
|
|
| Contract revenue |
$ 16,238
|
$ 10,298
|
$ 286
|
| Grant revenue |
1,109
|
1,650
|
1,337
|
| Total revenues |
17,347
|
11,948
|
1,623
|
| Costs and expenses |
|
|
|
| Research and development (including stock compensation expense of $1,192, $1,277 and $1,158 in 2016, 2015 and 2014, respectively) |
24,838
|
21,316
|
23,366
|
| General and administrative (including stock compensation expense of $1,676, $1,652 and $1,447 in 2016, 2015 and 2014, respectively) |
7,835
|
7,536
|
6,909
|
| Depreciation |
382
|
267
|
360
|
| Total costs and expenses |
33,055
|
29,119
|
30,635
|
| Gain from insurance proceeds, net |
682
|
|
|
| Loss from operations |
(15,026)
|
(17,171)
|
(29,012)
|
| (Expense) income from change in fair value of warrants, net |
(557)
|
772
|
6,591
|
| Other income (expense), net |
209
|
(61)
|
86
|
| Loss before income taxes |
(15,374)
|
(16,460)
|
(22,335)
|
| Income tax benefit |
37
|
38
|
253
|
| Net loss and comprehensive loss |
$ (15,337)
|
$ (16,422)
|
$ (22,082)
|
| Net loss per common share, basic |
$ (0.18)
|
$ (0.20)
|
$ (0.29)
|
| Weighted average shares outstanding, basic |
84,715,471
|
82,143,610
|
76,954,503
|
| Net loss per common share, diluted |
$ (0.18)
|
$ (0.20)
|
$ (0.31)
|
| Weighted average shares outstanding, diluted |
84,715,471
|
82,851,091
|
78,541,447
|