Accounting Policies - Net Loss and Number of Shares Used to Calculate Basic and Diluted Net Loss Per Share (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Numerator:                      
Net loss and comprehensive loss                 $ (15,337) $ (16,422) $ (22,082)
Less: income from change in fair value of warrants                   (332) (2,141)
Net loss attributable to common stockholders used to calculate diluted net loss per share                 $ (15,337) $ (16,754) $ (24,223)
Denominator:                      
Weighted-average shares outstanding - basic                 84,715,471 82,143,610 76,954,503
Potentially dilutive common shares outstanding:                      
Warrants                   707,000 1,586,000
Weighted-average shares used to calculate diluted net loss per share                 84,715,471 82,851,091 78,541,447
Basic - net loss per share $ (0.08) $ (0.07) $ (0.08) $ 0.06 $ 0.04 $ (0.08) $ 0.01 $ (0.16) $ (0.18) $ (0.20) $ (0.29)
Dilutive - net loss per share $ (0.10) $ (0.07) $ (0.08) $ 0.06 $ 0.04 $ (0.08) $ (0.05) $ (0.16) $ (0.18) $ (0.20) $ (0.31)