Background - Additional Information (Detail)
$ in Thousands
1 Months Ended 12 Months Ended
Feb. 28, 2017
USD ($)
Jan. 31, 2014
USD ($)
Dec. 31, 2016
USD ($)
Segment
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Accounting Policies and General Information [Line Items]            
Number of business segments | Segment     1      
Accumulated deficit     $ (318,279) $ (302,942)    
Cash and cash equivalents     $ 14,753 $ 23,027 $ 26,127 $ 31,948
Proceeds from common stock issued in public offerings   $ 18,800        
Subsequent Event [Member]            
Accounting Policies and General Information [Line Items]            
Proceeds from common stock issued in public offerings $ 20,900