Revenue from Contracts with Customers - Additional Information (Details)
$ in Thousands |
1 Months Ended |
3 Months Ended |
12 Months Ended |
|
Dec. 31, 2019
USD ($)
|
Nov. 30, 2019
USD ($)
|
Oct. 31, 2019 |
Jun. 30, 2018
USD ($)
|
Nov. 30, 2017
USD ($)
item
|
Dec. 31, 2019
USD ($)
|
Dec. 31, 2021
USD ($)
|
Dec. 31, 2019
USD ($)
|
Dec. 31, 2018
USD ($)
|
Dec. 31, 2017
USD ($)
|
| Disaggregation Of Revenue [Line Items] |
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| Total revenues |
|
|
|
|
|
|
|
$ 1,170,947
|
$ 1,094,274
|
$ 903,374
|
| License revenue |
|
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| Disaggregation Of Revenue [Line Items] |
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| Total revenues |
|
|
|
|
|
|
|
145,750
|
48,370
|
28,000
|
| Research and development revenue |
|
|
|
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|
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| Disaggregation Of Revenue [Line Items] |
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| Total revenues |
|
|
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|
|
|
|
$ 52,816
|
$ 68,895
|
$ 7,232
|
| Biogen |
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|
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| Disaggregation Of Revenue [Line Items] |
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| Up-front payment received |
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$ 28,000
|
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|
|
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| Additional cash payment received |
|
$ 150,000
|
|
$ 50,000
|
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| Number of initial performance obligations | item |
|
|
|
|
4
|
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| Discount Rate (As a percent) |
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8.00%
|
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| Biogen | License revenue |
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|
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| Disaggregation Of Revenue [Line Items] |
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|
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| Total revenues |
|
144,800
|
|
48,300
|
$ 27,000
|
|
|
|
|
|
| Biogen | Research and development revenue |
|
|
|
|
|
|
|
|
|
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| Disaggregation Of Revenue [Line Items] |
|
|
|
|
|
|
|
|
|
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| Total revenues |
|
5,200
|
|
1,500
|
900
|
|
|
|
|
|
| Biogen | Research and development revenue | Forecast |
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| Disaggregation Of Revenue [Line Items] |
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| Additional revenue expected |
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|
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$ 300
|
|
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| Biogen | Clinical Supply |
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| Disaggregation Of Revenue [Line Items] |
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| Total revenues |
|
|
|
200
|
100
|
|
|
|
|
|
| Biogen | License |
|
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|
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|
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| Disaggregation Of Revenue [Line Items] |
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| Total revenues |
$ 5,000
|
$ 150,000
|
|
$ 50,000
|
$ 28,000
|
|
|
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| Percentage of net sales in royalty payment |
|
|
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15.00%
|
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|
| Biogen | License | Commercial Supply Agreements |
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| Disaggregation Of Revenue [Line Items] |
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| Maximum percentage of product supplies on net sales |
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100.00%
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| Milestone payments received |
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$ 5,800
|
|
|
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| Milestone payments receivable |
$ 5,000
|
|
|
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|
$ 5,000
|
|
$ 5,000
|
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