Consolidated statements of operations and comprehensive loss - USD ($) $ in Thousands |
12 Months Ended | |
|---|---|---|
Dec. 31, 2021 |
Dec. 31, 2020 |
|
| Income Statement [Abstract] | ||
| Revenue from collaborations | $ 4,359 | |
| Operating expenses: | ||
| Research and development | 104,153 | $ 79,890 |
| General and administrative | 28,527 | 17,944 |
| Total operating expenses | 132,680 | 97,834 |
| Loss from operations | (128,321) | (97,834) |
| Interest and other (expense) income, net | 132 | (10,548) |
| Loss before income tax expense | (128,189) | (108,382) |
| Income tax expense | (143) | (161) |
| Net loss | (128,332) | (108,543) |
| Other comprehensive (loss) and income: | ||
| Gain (loss) on pension plans | 749 | (141) |
| (Loss) gain on available for sale investments | (109) | 68 |
| Comprehensive loss | $ (127,692) | $ (108,616) |
| Net loss per share, basic and diluted | $ (3.22) | $ (10.87) |
| Weighted average shares of common stock, basic and diluted | 39,855,403 | 9,988,191 |