Consolidated Statements of Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Revenue:    
Revenue $ 2,818 $ 5,416
Operating costs and expenses:    
Cost of goods sold 3,753 6,032
Research and development 4,095 4,017
Selling, general and administrative 30,935 36,330
Total operating costs and expenses 38,783 46,379
Loss from operations (35,965) (40,963)
Other income:    
Interest expense (2,291) (3,305)
Interest income and other income, net 124 583
Non-cash interest income on liability related to sale of future royalties 3,038 3,310
Total other income 871 588
Net loss before income taxes (35,094) (40,375)
Provision for income taxes 5 4
Net loss (35,099) (40,379)
Comprehensive loss $ (35,099) $ (40,379)
Net loss per share of common stock, basic and diluted (in dollars per share) $ (0.29) $ (0.47)
Shares used in computing net loss per share of common stock, basic and diluted –see Note 15 (in shares) 119,860,266 85,257,008
Product [Member]    
Revenue:    
Revenue $ 1,005 $ 2,521
Contract and Other Collaboration [Member]    
Revenue:    
Revenue $ 1,813 $ 2,895