Quarterly Financial Information (Unaudited) - Quarterly Financial Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |
3 Months Ended | 12 Months Ended | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Dec. 31, 2021 |
Sep. 30, 2021 |
Jun. 30, 2021 |
Mar. 31, 2021 |
Dec. 31, 2020 |
Sep. 30, 2020 |
Jun. 30, 2020 |
Mar. 31, 2020 |
Dec. 31, 2021 |
Dec. 31, 2020 |
Dec. 31, 2019 |
|
| Quarterly Financial Information Disclosure [Abstract] | |||||||||||
| Research and development | $ 4,506 | $ 4,591 | $ 9,227 | $ 5,642 | $ 2,347 | $ 1,891 | $ 1,103 | $ 1,541 | $ 23,966 | $ 6,882 | $ 9,674 |
| General and administrative | 2,609 | 2,102 | 2,075 | 2,342 | 2,374 | 1,863 | 1,815 | 1,816 | 9,128 | 7,868 | 6,854 |
| Total operating expenses | 7,115 | 6,693 | 11,302 | 7,984 | 4,721 | 3,754 | 2,918 | 3,357 | 33,094 | 14,750 | 16,528 |
| Other income (expense) | (36) | 2 | (9) | (15) | (3) | (10) | (4) | 37 | (58) | 20 | 133 |
| Net loss and comprehensive loss | $ (7,151) | $ (6,691) | $ (11,311) | $ (7,999) | $ (4,724) | $ (3,764) | $ (2,922) | $ (3,320) | $ (33,152) | $ (14,730) | $ (16,395) |
| Basic and diluted net loss per common share | $ (0.76) | $ (0.71) | $ (1.53) | $ (1.30) | $ (1.11) | $ (1.14) | $ (1.68) | $ (2.15) | $ (4.08) | $ (5.42) | $ (39.76) |