Avalon Ventures X, L.P.

Exempt (Private) Offering

Synthorx, Inc.: Statement of changes in beneficial ownership of securities

Synthorx, Inc.: Major Shareholders

Synthorx, Inc.: Statement of changes in beneficial ownership of securities

Synthorx, Inc.: Initial statement of beneficial ownership of securities

Otonomy, Inc.: Statement of changes in beneficial ownership of securities

Otonomy, Inc.: Initial statement of beneficial ownership of securities